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Zhuhaishi Shuangbojie Technology Co., Ltd.

Misoprostol, Mifepristone, Prostaglandin E1 manufacturer / supplier in China, offering Prohormone Steroids Misoprostol CAS 59122-46-2 for Antiulcerative, Nandrolone Decanoate (Deca Durabolin) Increase Androgen to Treat Anemia, Peptdies Powder Dsip Help Male Growth and Development 62568-57-4 and so on.

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Supplier Homepage Product Pharmaceutical Intermediates Prohormone Steroids Misoprostol CAS 59122-46-2 for Antiulcerative

Prohormone Steroids Misoprostol CAS 59122-46-2 for Antiulcerative

FOB Price: US $1 / G
Min. Order: 10 G
Min. Order FOB Price
10 G US $1/ G
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Production Capacity: 5000000kgs
Transport Package: 25kg/Drum
Payment Terms: T/T, Western Union, Money Gram, Bitcoin

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Basic Info
  • Model NO.: 59122-46-2
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >99%
  • Misoprostol Mf: C22h38o5
  • Misoprostol Einecs: N/a
  • Misoprostol Putity: 99% Min.
  • Delivery: Within 24 Hours Upon Receipt of Your Payment
  • Package: Professional Packing with Professional Materials
  • Specification: 99% min.
  • HS Code: 3001200010
  • Powder: Yes
  • Certification: USP
  • State: Solid
  • Misoprostol CAS: 59122-46-2
  • Misoprostol MW: 382.54
  • Misoprostol Appearance: Powder
  • Misoprostol Brand: Shuangbojie
  • Payment: T/T,Wu,Moneygram,Bitcoin Available
  • Trademark: Shuangbojie
  • Origin: China
Product Description
Misoprostol

Synonyms: CYTOTEC;9-OXO-11ALPHA,16-DIHYDROXY-16-METHYL-PROST-13E-EN-1-OIC ACID;9-OXO-11ALPHA,16-DIHYDROXY-16-METHYL-PROST-13E-EN-1-OIC ACID, METHYL ESTER;(11A,13E)-(-)-11,16-DIHYDROXY-16-METHYL-9-OXO-PROST-13-EN-1-OIC ACID METHYL ESTER;(11alpha,13e)-(+)-11alpha,16-dihydroxy-16-methyl-9-oxoprost-13e-en-1-oic acid methyl ester;(+/-)-15-DEOXY-[16RS]-16-HYDROXY-16-METHYLPROSTAGLANDIN E1;(+/-)-15-DEOXY-(16R,S)-16-HYDROXY-16-METHYL-PROSTAGLANDIN E1, METHYL ESTER;SC-29333
CAS: 59122-46-2
MF: C22H38O5
MW: 382.54

Chemical Properties White Solid
Usage antiulcerative;prostaglandin E1 analog that inhibits gastric acid secretion
Usage A cytoprotective prostaglandin PGE1 analogue
Biological Activity Cytoprotective prostaglandin E 1 analog that displays agonist activity at EP receptors. K i values are 120, 250, 67 and 67 nM at cloned mouse EP 1 , EP 2 , EP 3 and EP 4 receptors respectively. Prevents NSAID-induced gastric ulceration.

Misoprostol Usage:
Misoprostol is approved for use in the prevention of NSAID-induced gastric ulcers. It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric ulceration (e.g. with diclofenac in Arthrotec).

Misoprostol has other protective actions, but is only clinically effective at doses high enough to reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid suppression.
However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as effective as misoprostol,but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily doses (typically four) are the main issues impairing compliance with therapy.

Misoprostol is also used to prevent and treat post-partum bleeding. Orally administered misoprostol was marginally less effective than oxytocin. The use of rectally administered misoprostol is optimal in cases of bleeding; it was shown to be associated with lower rates of side effects compared to other routes. Rectally administered misoprostol was reported in a variety of case reports and randomised controlled trials. However, it is inexpensive and thermostable (thus does not require refrigeration like oxytocin), making it a cost-effective and valuable drug to use in the developing world. A randomised control trial of misoprostol use found a 38% reduction in maternal deaths due to post partum haemorrhage in resource-poor communities. Misoprostol is recommended due to its cost, effectiveness, stability, and low rate of side effects. Oxytocin must also be given by injection, while misprostol can be given orally or rectally for this use, making it much more useful in areas where nurses and physicians are less available.

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Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T Bank Transfer, Western Union and MoneyGram Available.
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.

Our advantage
1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;
3. Package: Professional packing with professional materials
4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days.
5. Service: Best Service with after-sales service and consultation
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