Anti-Aging USP Grade Pharmaceutical Peptide Epitalon
|FOB Price:||US $1 / Piece|
|Min. Order:||1 Piece|
|Min. Order||FOB Price|
|1 Piece||US $1/ Piece|
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|Payment Terms:||T/T, Western Union, Money Gram|
- Model NO.: 307297-39-8
- Customized: Non-Customized
- Suitable for: Elderly
- Purity: >99%
- Epitalon Payment Term: T/T, Western Union, Money Gram and Bitcoin
- Epitalon MOQ: 10g
- Specification: USP/BP
- HS Code: 123456
- Powder: Yes
- Certification: USP
- State: Powder
- Epitalon CAS: 307297-39-8
- Epitalon Delivery Time: Within 24hours After Your Payment
- Trademark: Shuangbojie
- Origin: China
Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in humans. This pineal peptide preparation is secreted in the epithlamium-epiphyseal region of the brain. Its more prominent tasks are: to regulate metabolism in the epiphysis, increase the sensitivity of hypothalamus to its natural hormonal influences, normalize the function of the anterior pituitary, regulate the levels of gonadotropins and melatonin in the body. Epithalamin increases a person's resistance to emotional stress and also acts as an antioxidant.
Epithalamin was first discovered in the late 1980's by Prof. Vladimir Khavinson from St. Petersburg, Russia. It has been studied extensively ever since. It is known by several names, including Epitalon, Epithalon, Epithalone, Epithalamin and Epithalamine. Since all the patents are held by the Russian inventor there is not much interest for this tetra-peptide from the western big pharma industry. This makes the substance fairly unknown in the west due to the absence of marketing usually seen with big pharma products. In Russia it is currently in clinical studies and shows prospective results as treatment for liver disorders, neuropathology, psychiatry and geriatrics.
Human life extenssion via Telomerase activation and elongation of Telomeres
Epitalon is one of the very few substances which are able to activate Telomerase (telomere terminal transferase) enzyme in humans. Telomerase renews (elongates) the telomeres, which are responsible for protection of the human DNA from damage and cancer causing errors.
Treatment of aging cells in culture with Epithalon induced elongation of telomeres to the size comparable to their length during the early cell divisions. Epitalon treated cells with elongated telomeres made 10 extra divisions (44 passages) in comparison with the control and continued dividing. Thus, Epithalon prolonged the vital cycle of normal human cells due to overcoming the Heyflick cell division limit. (reference: V. Khavinson et all. in Bulletin of Experimental Biology and Medicine. June 2003, PMID: 12937682)
Epitalon used for Anti Aging
Epitalon decreases the age-related changes in immune and neuroendocrine systems, reduces the incidence of recurrent infections and chronic diseases. Long term clinical trials have shown that in patients with age-related pathology Epithalamin eliminates imbalance in prooxidation and antioxidation systems. (reference: N. Anisimov et all. Neuroendocrinology Letters, 2011, PMID: 11335874)
Results of 12-months treatment with Epithalon in patients with signs of accelerated aging showed normalizing effect on metabolism and condition of various functional systems. Elevated uric acid, alkaline phosphatase and cholesterol in elder patients returned to normal after 10 days of treatment, and remained stable in a several months peroid afterwards.
Experimental and clinical studies of Epitalon showed the following pharmaclogical properties of Epithalamin (Epitalon):
Telomerase activation (consequently, elongation of Telomeres)
regulates neuroendocrinous system
increases the hypothalamic sensitivity to the endogenous hormonal effects
decrease or suppression of proliferative changes in vaginal epithelium and endometrium in anovulatory phase
normalization of gonadotropic hormones levels (FSG, LG, prolactin)
positive influence on peripheral haemodynamics: improvement of blood rheology, decrease of intravessel thrombogenesis
regulation of the levels of reactants in the acute inflammation phase (c3-component of the complement, pre-albumin, C-reactive protein, alpha-orosomucoids
normalization of T-cell immunity
normalization of aqua-electrolyte balance indices
normalization of uric acid levels
normalization of Cholesterol
rejuvenation / strengthening of the immune system
inhibition of spontaneous and induced carcinogenesis (tumor prevention)
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|TMT Blend 375||Trenbolone Enanthate 125mg/ml Drostanolone Enanthate 125mg/ml Testosterone Enanthate 125mg/ml|
|TM Blend 500||Trenbolone Enanthate 250mg/ml Drostanolone Enanthate 250mg/ml|
A peptide that I purchased recently has less powder in it than others I've gotten. Does this mean it doesn't have the right MG?
Peptides due to their nature come in a variety of sizes and shapes. Normally after the lyophilization process has completed we have a peptide that is in a perfect cake. However there are times when it may break in transit or simply appear differently. This is no way effects the quality or potency of the product. It is simply an aesthetic issue. While we do try to always present a product that looks perfect, on occasion this isn't possible. Proteins such as LR3 are very large in size and due to the requirement of a buffer will appear larger in size than a mod grf or ghrp. This is also normal.
If A Peptide Is 98% In Purity Then What Is The Remaining 2%?
The purity level indicated on a COA is simply a measurement of aminos that made it into the proper chain to form the peptide. The left over 2% are simply aminos that, for what ever reason, didn't make it into the proper sequence.
What Are The Purity Levels Of The Peptides You Sell?
AP PEPTIDE will never sell a peptide that is less than 98% in purity from our catalog section. Many of our smaller peptide chains are well into the 99% purity range. We have manufacturing abilities that are quite often beyond the scope of smaller companies and therefore are able to achieve very high purity levels. Proteins such as IGF-1 LR3 are always receptor grade and always above 95% purity.
Two Vials Of The Same Peptide Have Different Amounts Of Powder. Does This Mean They Are Different In Milligrams?
Peptides, due to their nature, come in a variety of sizes and shapes. Normally after the lyophilization process has completed we have a peptide that is in a perfect cake. However there are times when it may break in transit or simply appear differently. This in no way effects the quality or potency of the product. It is simply an aesthetic issue. While we do try to always present a product that looks perfect, on occasion this isn't possible.
Proteins are very large in size and due to the requirement of a buffer will appear larger in size than a mod grf or ghrp. This is also normal.
What Are Your Products Used For?
Peptides and Research serums are manufactured and sold to be used in a laboratory research setting. None of our products are intended for, nor are they manufactured for, diagnostic or therapeutic purposes in humans. Strong Peptide reserves the right to require additional verification of proper intent prior to fulfilling orders. Any orders that we feel aren't for the specific intended purpose laid out in our Terms and Conditions will be denied. Truthfully, if you are asking this question then you shouldn't be ordering from AP PEPTIDES.
How should I store and handle my peptides?
Because peptides are hygroscopic, warm up the peptide to room temperature in a desiccator prior to opening and weighing out the portion of the peptide to be used. Failure to do so can cause condensation to form on the product when the bottle or vial is opened and greatly reduce the stability of the material. Weigh out quickly in a clean environment only the needed quantity of the peptide to be used to minimize contamination and reseal container tightly. Store all unused peptide at -20° C or less in a sealed container with desiccant. Storage under these conditions will reduce and prevent bacterial degradation, secondary structure formation, and oxidation for up to several years. Sequences containing cysteine, methionine, tryptophan, asparagine, glutamine, and N-terminal glutamic acid will have a shorter shelf life than other peptides.
When solubilizing the peptide, please use the recommended solvents outlined in the solubility test provided by AP if your experimental conditions will allow it. Sonication is often helpful to dissolve the peptide. In general, sterilized water is the preferred solvent, but acidic peptides will dissolve in a basic buffer and basic peptides in an acidic buffer as determined by the amino acid sequence of the peptide. Peptide sequences containing Cys, Met, and Trp require oxygen free solvents as they are especially prone to oxidation. Peptides in solution are much less stable than lyophilized form and will remain viable for a much shorter period of time. As such, it is not recommended to store peptides under these conditions, but if absolutely unavoidable, the peptides in solution should be kept at -20° C using sterile buffers at pH 5-6 to prolong shelf life.