Pharmaceutical Raw Materials Pregabalin CAS 148553-50-8 for Treat Pain
|FOB Price:||US $1 / G|
|Min. Order:||10 G|
|Min. Order||FOB Price|
|10 G||US $1/ G|
|Payment Terms:||T/T, Western Union, Money Gram, Bitcoin|
- Model NO.: 148553-50-8
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >99%
- Pregabalin Mf: C8h17no2
- Pregabalin Einecs: N/a
- Pregabalin Putity: 99% Min.
- Delivery: Within 24 Hours Upon Receipt of Your Payment
- Mode: Door to Door
- Specification: 99% min.
- HS Code: 3001200010
- Powder: Yes
- Certification: USP, BP
- State: Solid
- Pregabalin CAS: 148553-50-8
- Pregabalin MW: 159.23
- Pregabalin Appearance: Powder
- Pregabalin Brand: Shuangbojie
- Payment: T/T, Wu, Moneygram, Bitcoin
- Trademark: Shuangbojie
- Origin: China
Synonyms: 3(S)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID;(3S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID;PREGABALIN;Pregablin;3-(Aminomethyl)-5-methyl-hexanoic acid;PREDNISOLONESODIUMPHOSPHATE;(R)-Pregabalin;(S)-Pregabalin
Chemical Properties Off-White Solid
Usage S-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia.
Pregabalin belongs to a group of medicines known as anti-epileptic medicines, although it is prescribed for the treatment of several different conditions. You may have been prescribed it for the treatment of partial seizures, which is a type of epilepsy. A seizure is a short episode of symptoms which is caused by a burst of abnormal electrical activity in the brain. With a partial seizure, the burst of electrical activity stays in one part of the brain. Therefore, you tend to have localised or 'focal' symptoms. Pregabalin works by reducing the abnormal electrical activity in the brain. It is taken alongside other medicines for epilepsy.
Pregabalin is also prescribed to treat certain types of long-lasting pain caused by damage to nerves. This type of pain, called neuropathic pain, can be caused by a number of different conditions, including diabetes (where it is called diabetic neuropathy) and shingles(where it is called postherpetic neuralgia).
Pregabalin is described chemically as (S)-3-(aminomethyl)-5-methylhexanoic acid. The molecular formula is C8H17NO2 and the molecular weight is 159.23.
Pregabalin is a white to off-white, crystalline solid with a pKa1 of 4.2 and a pKa2 of 10.6. It is freely soluble in water and both basic and acidic aqueous solutions. The log of the partition coefficient (n-octanol/0.05M phosphate buffer) at pH 7.4 is 1.35.
LYRICA (pregabalin) Capsules are administered orally and are supplied as imprinted hard-shell capsules containing 25, 50, 75, 100, 150, 200, 225, and 300 mg of pregabalin, along with lactose monohydrate, cornstarch, and talc as inactive ingredients. The capsule shells contain gelatin and titanium dioxide. In addition, the orange capsule shells contain red iron oxide and the white capsule shells contain sodium lauryl sulfate and colloidal silicon dioxide. Colloidal silicon dioxide is a manufacturing aid that may or may not be present in the capsule shells. The imprinting ink contains shellac, black iron oxide, propylene glycol, and potassium hydroxide.
Pregabalin How to use
LYRICA (pregabalin) oral solution, 20 mg/mL, is administered orally and is supplied as a clear, colorless solution contained in a 16 fluid ounce white HDPE bottle with a polyethylene-lined closure. The oral solution contains 20 mg/mL of pregabalin, along with methylparaben, propylparaben, monobasic sodium phosphate anhydrous, dibasic sodium phosphate anhydrous, sucralose, artificial strawberry #11545 and purified water as inactive ingredients.
Pregabalin is used for:
Treating fibromyalgia or nerve pain caused by certain conditions (eg, shingles, diabetic nerve problems, spinal cord injury). It is also used in combination with other medicines to treat certain types of seizures. It may also be used for other conditions as determined by your doctor. Pregabalin is an anticonvulsant and neuropathic pain agent. Exactly how pregabalin works is not known. It is thought to bind to certain areas in the brain that help reduce seizures, nerve pain, and anxiety.
How to use pregabalin:
1. Pregabalin comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get pregabalin refilled.
2. Take pregabalin by mouth with or without food.
3. Take pregabalin on a regular schedule to get the most benefit from it.
4. Taking pregabalin at the same time each day will help you remember to take it.
5. If you miss a dose of pregabalin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Before using pregabalin:
Some medical conditions may interact with pregabalin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have heart problems (eg, congestive heart failure, irregular heartbeat), high blood pressure, muscle problems, diabetes, or bleeding problems or low platelets
if you have kidney problems or are on dialysis
if you have a history of mental or mood problems (eg, depression), suicidal thoughts or attempts, or alcohol or drug abuse.
|Appearance||A white to off white powder||White powder|
|Identification||A. Meets the requirement||Complies|
|B. IR: similar to Reference Substance||Complies|
|Loss on drying||≤0.5%||0.21%|
|Related Substances||Any single impurity ≤0.1%|
Total impurity ≤0.8%
|Purity By HPLC R-isomer||≤0.15%||0.10|
|Residue on ignition||≤0.1%||0.05%|
|Residual solvents||Isopropyl alcohol ≤5000ppm|
Ethyl Acetate ≤5000ppm
|Conclusion||Analyse according to Factory Standard , Conform|
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