Bp Tranexamic Acid High Purity Amstat CAS 1197-18-8 Raw Pharma API
|FOB Price:||US $9.9 / kg|
|Min. Order:||10 grams|
|Min. Order||FOB Price|
|10 grams||US $9.9/ kg|
|Production Capacity:||5, 900kg/Month|
|Transport Package:||Super Discreet and Secure|
|Payment Terms:||T/T, Paypal, Money Gram, Western Union, Bitcoin|
- Model NO.: Tranexamic Acid
- CAS: 1197-18-8; 701-54-2
- Appearance: White Crystalline Powder
- Stock: Mass and Plenty (Sample Available)
- Shipping: Average 6 Days / Door-to-Door
- Trademark: SBJ
- Origin: China
- Product Name: Tranexamic Acid / Amstat
- Purity: 99.95% Bp2012 Standard
- Advantage: 14 Years Old Manufacturer / Lowest Price
- Lead Time: Within 12 Hours After Payment Confirmed
- Pass Rate: 100% Ensured by Rich Exporting Experiences
- Specification: BP2012
- HS Code: 3001200020
Attention: China 14 years old Manufacturer direct selling; Gold Member, Gold Quality; Lowest price served; Mass and plenty in stock now ; Sample and COA are available at any time; Prompt shipment after payment confirmed; Re-send policy; 5% discount for second same order.
Product on Sell: Tranexamic Acid
Synonyms: TIMTEC-BB SBB006715;TRANS-4-AMINOMETHYL-1-CYCLOHEXANECARBOXYLIC ACID;trans-4-aminomethylcyclohexane-1-carboxylate;TRANS-4-(AMINOMETHYL)CYCLOHEXANECARBOXYLIC ACID;TRANEXAMIC ACID;amstat;amcha;amikapron
Categories: 4-Substituted Cyclohexane Carboxylic Acids;APIs;Amines;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Building Blocks;C8;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Organic Building Blocks;API;CYKLOKAPRON;Cosmetics;Hemostatic;Pharmaceutical raw materials
Appearance: White crystalline powder
Solubility: Soluble in water and glacial acetic acid, almost not soluble in ethanol and acetone (96%)
Shelf Life: 4 Years
Usage: Antifibrinolytic agent; blocks lysine binding sites of plasminogen. Hemostatic.
Used as a lysine analogue to characterize binding sites in plasminogen.1,2
Tranexamic Acid Test Report(COA):
|Test Items||Specification||Test Results|
|Appearance||White crystalline powder||White crystalline powder|
|Solubility||Soluble in water and glacial acetic acid, almost not soluble in ethanol and acetone (96%)||Soluble in water and glacial acetic acid, almost not soluble in ethanol and acetone (96%)|
|Identification||Infrared absorption map complies with the tranexamic acid comparison map||Infrared absorption map complies with the tranexamic acid comparison map|
|Loss on drying||≤0.5%||0.09%|
|Residue on ignition||≤0.1%||0.01%|
|Related substances||A≤0.1%, B≤0.2% C ≤ 0.1%, D ≤ 0.1%||A≤0.1%, B≤0.2% C ≤ 0.1%, D ≤ 0.1%|
|Total impurities||(except A,B) ≤0.2%||Total impurities(except A,B)=0.015%|
|Conclusion||Complies with BP2012|
Description and Application:
Tranexamic acid (TXA) is used to treat or prevent excessive blood loss from trauma, surgery, and in various medical conditions including hemophilia and heavy menstrual bleeding. It comes in oral and intravenous forms.
It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.
Tranexamic acid is frequently used following major trauma. Tranexamic acid is used to prevent and treat blood loss in a variety of situations, such as dental procedures for hemophiliacs, heavy menstrual bleeding, and surgeries with high risk of blood loss.
Tranexamic acid has been found to decrease the risk of death in people who have significant bleeding due to trauma. However, its benefit only appears to be within the first three hours.
Heavy menstrual bleeding---
Tranexamic acid is used treat heavy menstrual bleeding. When taken by mouth it is both safely and effectively treated regularly occurring heavy menstrual bleeding. Another study demonstrated that the dose does not need to be adjusted in people who are between ages 12 and 16.
Tranexamic acid is used in orthopedic surgery to reduce blood loss, to the extent of reducing or altogether abolishing the need for perioperative blood collection. It is of proven value in clearing the field of surgery and reducing blood loss when given before or after surgery. Drain and number of transfusions are reduced. However, the hidden blood loss is not reduced. Still, it is becoming an important tool in the anaesthetist's arsenal. It is commonly used in joint replacement surgery.
Use of tranexamic acid in surgical corrections of craniosynostosis in children reduces the need for blood transfusions.
Tranexamic acid is commonly used in cardiac surgery, both with and without cardiopulmonary bypass. It replaces aprotinin.
In the United States, tranexamic acid is FDA approved for short-term use in people with severe bleeding disorders who are about to have dental surgery. Transexamic acid is used for a short period of time before and after the surgery to prevent major blood loss and decrease the need for blood transfusions. In people with hemophilia, combinations of tranexamic acid and factor VII or IX have effectively decreased blood loss and the need for transfusions after dental surgery In one person with mild hemophilia, a combination of tranexamic acid and demopressin effectively stopped bleeding
Tranexamic acid is used in dentistry in the form of a 5% mouth rinse after extractions or surgery in patients with prolonged bleeding time, e.g. from acquired or inherited disorders.
In obstetrics, tranexamic acid is used after delivery to reduce bleeding, often with syntocinon/oxytocin and fundal massage. A major trial is in progress worldwide to establish the efficacy of the drug to arrest postpartum haemorrhage (PPH). Since the drug can be administered orally, it has great potential to reduce maternal mortality rates in developing countries where primary healthcare is often unavailable.
In cardiac surgery, e.g. coronary artery bypass surgery, it is used to prevent excessive blood loss.
In spine surgery, e.g. scoliosis correction with posterior spinal fusion using instrumentation, to prevent excessive blood loss.
In hereditary angioedema
In hereditary hemorrhagic telangiectasia - Tranexamic acid has been shown to reduce frequency of epistaxis in patients suffering severe and frequent nosebleed episodes from hereditary hemorrhagic telangiectasia.
In melasma - Tranexamic acid has shown to provide rapid and sustained lightening in melasma by decreasing melanogenesis in epidermal melanocytes.
In hyphema - Tranexamic acid has been shown to be effective in reducing risk of secondary hemorrhage outcomes in patients with traumatic hyphema.
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|Shipping time||Average 6 working days (Door-to-Door)|
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5. COA (by HPLC) and sample are available at any time.
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