Ace-031 1mg White Lyophilized Powder Ace 031 for Bodybuilding 1mg/Vial
|FOB Unit Price:||US $1 US $2|
|Purchase Qty. (vial)||FOB Unit Price|
|Transport Package:||Foil Bags, Cardboard Drum or Disecret Packages|
|Payment Terms:||T/T, Western Union, Money Gram, Bitcoin|
- Model NO.: Ace-031
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >98%
- Usage: Increases Muscle Mass and Strength
- Assay: 99%
- Payment: T/T, Western Union, Money Gram, Bitcoin
- Delivery Time: Within 24 Hours After Payment
- Advantage: 15 Years in The Field
- Specification: ISO9001
- HS Code: 2942000000
- Powder: Yes
- Certification: GMP, USP, BP
- State: Solid
- Name: Ace 031
- Appearant: Lyophilized Powder
- Place of Origin: China
- Delivery: EMS, DHL, TNT, FedEx, UPS
- Market: Global
- Trademark: Shuangbojie
- Origin: China
1. Ace-031 Purchase Notes:
1). All orders are guaranteed 100% success delivery;
2). All orders will have tracking number to trace online;
3). All orders will be sent out within 24hrs after payment (weekend is not included);
4). All products unit prices are fluctuating automatically according to order quantity,the more quantities,the lower prices;
5). Anyone wants order sent by DHL,TNT or FedEx,you can contact us directly by email,specific shipping cost will be quoted for you;
6). All orders can be shipped to following countries: UK, Canada, U.S.A, Australia, the Netherlands, Spain, England, United States, Russia, China, Singapore, Poland, France, Germany, Switzerland, Sweden, Denmark, Norway, Portugal, Italy, Greece, India, Thailand, Indonesia, Malaysia, New Zealand, Brazil, Argentina, Mexico, South Africa, Korea, Iran, Ukraine, Czech, Houston and Worldwide.
2. Ace-031 Details:
|Ace-031 Purity||> 99%|
|Ace-031 Storage temperature:||2-8 Celsius degree|
|Ace-031 Quality guarantee period:||2 years in 2-8 Celsius degree|
|Ace-031 Vial color:||transparent color / Top color: blue/green/red/yellow/ customized|
|Ace-031 Physical Appearance:||freeze-dried powder in white|
|Ace-031 Place of origin:||China|
|Ace-031 Certification:||HPLC, MSDS|
3. Ace 031 Description
ACE-031, a soluble fusion protein based on the activin receptor type IIB (ActRIIB), is a biologic therapeutic that inhibits signaling through the ActRIIB receptor. By preventing signaling though ActRIIB, ACE-031 increases muscle mass and strength. In numerous and varied animal models of disease, ACE-031 significantly increased muscle mass and muscle strength. ACE-031, and a related molecule ACE-435, have shown encouraging preclinical results in animal models of age-related muscle loss, neuromuscular disease, cancer treatment-related muscle loss and metabolic diseases. ACE-031 is currently being studied in a Phase 1 multiple dose clinical trial in healthy volunteers. ACE-435 is expected to enter clinical trials in 2010.
4. ACE-031 Cook Recipes:
Add 1 ml of sterile diluent and let the lyophilized pellet dissolve completely.
5. ACE-031 Stability:
Store lyophilized protein at -20 °C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 °C for a limited period of time. The lyophilized protein remains stable until the expiry date when stored at -20 °C.
6. How ACE-031 works?
1) CE-031 is a fusion protein that is soluble and is known to have a positive feedback mechanism in the increasing muscle strength and mass. The polypeptide is under research for the treatment of various condition and diseases such as metabolic diseases, cardiovascular anomalies, renal neoplasms during childhood, cancer, age related muscle loss and other neuromuscular diseases. ACE-031 is biopeptide that has therapeutic properties that are mainly based on the activin receptor type 2 or ActRIIB. The polypeptide inhibits cell signaling by blocking ActRIIB receptor thereby increasing muscle strength and mass. It is an artificially synthesized polypeptide of the natural antibody and a part of the ActRIIB receptor. When recombinant technology is used to fuse the proteins, it eliminates myostatin and other biomolecules that limit muscle growth and strength. ACE-031 is classified under the category of proteins in the TGF-beta super family, which are essential in the regulation of muscle growth and strength.
2) ACE-031 mechanism of action is through the switching on and up regulation of the muscle growth process, experimental studies reveal that the polypeptide acts by inhibiting the ActRIIB receptor and promotes myoblasts differentiation, development, and maturity. According to studies administration of ACE-031 for 2 weeks increases skeletal muscle density, increases adiponectin levels and reduces leptin level in the system. The polypeptide is composed of 368 amino acids in the sequence; this makes a very large and complex polypeptide. Muscle growth is mainly accentuated by the production of muscle cells and this occurs via the amino acids and other essential components. TGF beta protein super family, which is the main regulator in the switching on and off the muscle development through the amino acids. When the ActRIIB receptors interact with GDF-8, it causes a signal transduction which in causes the initiation of myoblasts differentiation, development and maturity.
3) ACE-031 is a protein under research for enhancing muscle cell differentiation in a recombinant fusion is vital in inhibiting factors that limit muscle growth and generation of myoblasts by endogenous binding to the cells. The blockage of the antagonist causes an enhanced production of myoblasts, muscle function and improved muscle strength. The mechanism can prove to be essential in dealing with problems such as muscular dystrophy, androgen deprivation, and muscle loss associated with corticosteroids among other conditions. Unlike the generation of mutation specific ribonucleotide based therapy, the clinical development for Duchene muscular dystrophy or what is commonly called DMD, ACE-031 can be very beneficial because it is not affected by existing mutations.
7. Polypeptide We Supply:
|CJC-1295 with DAC||2mg/vial||Oxytocin||2mg/vial|
|CJC-1295 without DAC||2mg/vial||TB500||2mg/vial|
1). Payment: West union. Moneygram . Bank transfer. Bitcoin
2). Packing: under 20kg in discreet packing or customized. Above 50kg, If need, ship by air or sea is
also OK. Full set of documents are available.
3). Delivery: DHL, EMS, UPS, TNT, FedEX
4). Delivery time: in 24 hours after payment.