Anti-Paining Local Anesthetic Powder Prilocaine CAS 721-50-6 Pain Killer
|FOB Unit Price:||US $1 US $2|
|Purchase Qty. (g)||FOB Unit Price|
|Transport Package:||Foil Bag or Tin|
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- Model NO.: 721-50-6
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >98%
- Einecs: 211-957-0
- MW: 220.31
- Melting Point: 37-38ºC
- Delivery Time: Within 24 Hours After Your Payment
- Express: UPS, TNT, DHL, EMS, Hkems, FedEx
- Specification: ISO9001
- HS Code: 3006920000
- Powder: Yes
- Certification: ISO 9001
- State: Solid
- CAS: 721-50-6
- Mf: C13h20n2o
- appearance: Needle Like Crystal
- Boiling Point: 159-162ºC(0.133kpa)
- Payment Terms: Western Union, Moneygram, Tt and Bitcoin
- Trademark: Shuangbojie
- Origin: China
Molecular formula: C13H20N2O
Molecular weight: 220.31
Appearance: White crystalline powder.
Uses: Used in all sorts of anesthesias of Epidural, block and infiltration.
Packing: 1kg/5kg Aluminum foil bag; 25KG Cardboard drum.
Mol File: 721-50-6.mol
Quality Standard: Pharmaceutical grade
Category: Pharmaceutical raw material
Chemical properties:acicular crystallization. The melting point of 37-38 degrees, 159-162 degrees (0.133kPa) of boiling point, refractive index (nD20) 1.5299. The hydrochloride ([1786-81-8]) is a white crystalline powder. Temperature 167-168 degrees. Soluble in water and ethanol, slightly soluble in chloroform. Sour bitter taste, no smell.
Usage:Pharmaceutical Intermediates .
White crystalline powder
Aluminum foil bag inside+ Carton box outside;1kg/bag,25kg/drum;
Store in sealed containers at cool & dry place. Keep away from light, moisture, pest infestation.
Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).
Prilocaine topical is a local anesthetic (numbing medication). It works by blocking nerve signals in your body.
Prilocaine topical is used to numb the skin, or surfaces of the penis or vagina, in preparation for a medical procedure or to lessen the pain of inserting a medical instrument such as a tube or speculum.
Usage And Synthesis:
Prilocaine belongs to amide local anesthetic drug with its anesthesia intensity and speed being similar as lidocaine but with a longer duration period and weaker effect on vasodilation. It has a lower toxicity than lidocaine. It is clinically for local anesthesia, especially suitable for treating patients who are not allowed to use adrenaline.
Its 3% solution has a similar local anesthesia efficacy as the anesthesia drug of 2% lidocaine together with adrenaline. It has a slow onset time which lasts about 6 ~ 7min and the duration time of about 1.5 ~ 2h. It has a strong penetration capability through mucous membranes. Adrenaline has a slightly prolonged duration of action. PPB is 55% and T1/2 of about 1.5h. It is subject to liver metabolism with its metabolites nitroso toluidine being able to oxidize hemoglobin to form methemoglobin. It can be transported to the fetus through the placenta.
once the usage amount exceeds 600mg, methaemoglobinaemia can occur with cyanosis, tachycardia, headache, dizziness and weakness occurring.
patients of anemia, congenital or acquired methaemoglobinaemia, respiratory failure or heart failure and hypoxic patients should be disabled. It is forbidden for applied to obstetric anesthesia.
Usage and dosage:
infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours.
Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.
Epidural anesthesia: use10 to 30 mL of 1.5% ~ 1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.
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